Gilles Vassal Selected Research

CGP 74588

11/2008	Population pharmacokinetics and pharmacogenetics of imatinib in children and adults.
10/2006	Pharmacokinetic-pharmacodynamic relationships of imatinib and its main metabolite in patients with advanced gastrointestinal stromal tumors.

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Gilles Vassal Research Topics

Disease

128	Neoplasms (Cancer) 06/2022 - 02/2002
29	Neuroblastoma 04/2022 - 11/2003
19	Glioma (Gliomas) 01/2022 - 02/2002
10	Glioblastoma (Glioblastoma Multiforme) 04/2022 - 10/2002
9	Brain Neoplasms (Brain Tumor) 01/2015 - 12/2002
6	Medulloblastoma 04/2022 - 05/2003
6	Neoplasm Metastasis (Metastasis) 10/2019 - 03/2005
6	Ependymoma 03/2015 - 07/2002
5	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 05/2004
4	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 03/2003
4	Leukemia 01/2020 - 03/2003
4	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2009
4	Carcinogenesis 07/2014 - 07/2008
3	Lymphoma (Lymphomas) 11/2021 - 03/2013
3	Disease Progression 01/2021 - 01/2020
3	Thrombocytopenia (Thrombopenia) 01/2021 - 02/2007
3	Rhabdomyosarcoma 01/2020 - 02/2007
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 11/2006
3	Infections 01/2020 - 10/2002
3	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2015 - 10/2006
3	Nausea 02/2013 - 02/2007
3	Body Weight (Weight, Body) 04/2012 - 11/2008
3	Gliosarcoma 09/2009 - 12/2002
2	Hodgkin Disease (Hodgkin's Disease) 01/2022 - 03/2003
2	Carcinoma (Carcinomatosis) 01/2021 - 07/2011
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 10/2020 - 01/2018
2	Second Primary Neoplasms (Neoplasms, Second) 01/2020 - 08/2017
2	Iron Overload 01/2016 - 04/2012
2	Necrosis 01/2016 - 05/2006
2	Diffuse Intrinsic Pontine Glioma 07/2015 - 01/2012
2	Vomiting 02/2012 - 02/2007

Drug/Important Bio-Agent (IBA)

28	Pharmaceutical PreparationsIBA 01/2022 - 02/2002
14	Proteins (Proteins, Gene)FDA Link 06/2022 - 11/2003
13	Temozolomide (Temodar)FDA LinkGeneric 04/2022 - 11/2006
11	Biological ProductsIBA 01/2022 - 03/2005
9	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2002
8	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2021 - 05/2003
8	CrizotinibIBA 11/2021 - 01/2016
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2010
6	Phosphotransferases (Kinase)IBA 06/2022 - 09/2009
6	Vincristine (Oncovin)FDA LinkGeneric 11/2021 - 06/2012
6	Etoposide (VP 16)FDA LinkGeneric 11/2021 - 03/2003
6	Topotecan (Hycamtin)FDA LinkGeneric 11/2021 - 10/2010
6	Tyrosine Kinase InhibitorsIBA 01/2020 - 02/2008
5	Alkylating AgentsIBA 04/2022 - 03/2003
5	Irinotecan (Camptosar)FDA LinkGeneric 01/2015 - 10/2003
5	Imatinib Mesylate (Gleevec)FDA Link 02/2013 - 10/2006
5	ErbB Receptors (EGF Receptor)IBA 11/2011 - 07/2008
4	AntibodiesIBA 01/2022 - 01/2008
4	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2013
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2021 - 06/2005
4	Anaplastic Lymphoma KinaseIBA 11/2021 - 01/2016
4	Cisplatin (Platino)FDA LinkGeneric 10/2019 - 09/2008
4	Busulfan (Busulfex)FDA Link 01/2017 - 02/2007
4	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 07/2015 - 09/2009
3	larotrectinibIBA 06/2022 - 11/2020
3	TropomyosinIBA 06/2022 - 11/2020
3	Cell-Free Nucleic AcidsIBA 01/2022 - 01/2016
3	Epidermal Growth Factor (EGF)IBA 01/2022 - 05/2008
3	Rituximab (Mabthera)FDA Link 11/2021 - 01/2020
3	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2018
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020 - 01/2015
3	Carboplatin (JM8)FDA LinkGeneric 01/2017 - 09/2008
3	Antineoplastic Agents (Antineoplastics)IBA 01/2015 - 05/2003
3	EnzymesIBA 02/2013 - 08/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2011 - 11/2003
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2011 - 02/2008
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 07/2011 - 09/2009
3	Gemcitabine FDA Link 01/2011 - 10/2007
2	Everolimus FDA Link 11/2021 - 11/2011
2	Mechanistic Target of Rapamycin Complex 1IBA 11/2021 - 01/2017
2	Sirolimus (Rapamycin)FDA Link 11/2021 - 06/2011
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2021 - 11/2011
2	Circulating Tumor DNAIBA 01/2021 - 01/2019
2	regorafenibIBA 01/2021 - 01/2015
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2020
2	NivolumabIBA 01/2021 - 01/2018
2	130-nm albumin-bound paclitaxelIBA 01/2020 - 01/2018
2	Angiogenesis InhibitorsIBA 01/2020 - 06/2011
2	cabozantinibIBA 01/2017 - 07/2015
2	Melphalan (Alkeran)FDA LinkGeneric 01/2017 - 01/2016
2	Axitinib (AG 013736)IBA 01/2017 - 06/2011
2	dipinacoline glutamateIBA 07/2015 - 01/2012
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 03/2015 - 04/2009
2	Monoclonal AntibodiesIBA 08/2014 - 12/2010
2	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 06/2012 - 11/2011
2	Chemokine CXCL12IBA 01/2012 - 10/2007
2	Phosphatidylinositols (Phosphatidylinositol)IBA 11/2011 - 11/2010
2	TensinsIBA 11/2011 - 01/2011

Therapy/Procedure

39	Therapeutics 01/2022 - 10/2002
21	Investigational Therapies (Experimental Therapy) 01/2021 - 09/2009
18	Drug Therapy (Chemotherapy) 01/2022 - 03/2003
14	Radiotherapy 01/2022 - 10/2002
6	Precision Medicine 01/2022 - 01/2017
4	Immunotherapy 01/2022 - 06/2005
4	Injections 05/2005 - 02/2002
2	Surgical Amputation (Amputations) 06/2022 - 08/2017
2	Salvage Therapy 01/2022 - 01/2011
2	Immunomodulation 01/2021 - 01/2020
2	Hematopoietic Stem Cell Transplantation 04/2012 - 05/2008